VRF stands for variable refrigerant flow. It is a heating and cooling system built around one — or a few — outdoor condensing units that feed refrigerant to many indoor units, and the whole idea is in the name: the system varies how much refrigerant it sends to each indoor unit, moment to moment, so every room gets exactly the amount of heating or cooling it needs and nothing more.
You will also hear it called VRV. That is not a different technology — VRV (variable refrigerant volume) is simply Daikin's trademarked name for the same idea, coined when the company introduced it in the 1980s. Because the term is protected, other makers like Mitsubishi, LG, and Samsung call their systems VRF. When a contractor says VRV, they mean a Daikin-style VRF system.
If a ductless mini-split is the small version of this idea — one outdoor unit, a handful of indoor heads — then VRF is the building-scale version: dozens of indoor units on a single refrigerant loop, each independently controlled, with far more capacity and smarter load-sharing. Here is how it works, and where it earns its keep.